Facilities and Instrumentation
Proteomics is a “biological assay” that exploits protein biochemistry and it techniques for protein separations and analysis in order to perform a reproducible qualitative or quantitative comparative analysis of a complex mixture of proteins. Proteomic analysis involves several highly demanding techniques and technologies. These include protein separations, computer assisted analysis, protein mass spectrometry and bioinformatics. NextGen Sciences, Inc. has established a laboratory that is capable of approaching the many challenges in proteomics. The major challenges faced by scientists in this field are protein complexity and dynamic range, biological variation, absolute technical reproducibility, lack of truly high throughput methods, interpretation of mass spectra for protein identification and characterization of post-translational modifications (PTM) by mass spectrometry. The labs at NextGen Sciences, Inc. are equipped with many platforms for proteomic analysis since many complimentary techniques should be utilized to help overcome some of these challenges.
The facility has individual environmental control systems for each of the labs. These insure constantly controlled temperature, humidity and air quality (HEPA filtration). All instruments and computers are on A/C uninterrupted power source that is backed up by a natural gas-powered generator. The servers are on weekly scheduled automatic backup in which the hard drives are replicated onto external 300GB hard drives.
NextGen Sciences Key Capabilities and Instrumentation
| Protein Separations |
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| 2-D Gel Separations |
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| Enzymatic Digestion of Proteins |
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| Mass Spectrometry |
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| MS Software |
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| Sample Storage |
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| General |
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